What is innovation in vitro sciences?


MatTek Corporation was founded in 1985 by two chemical engineering professors from MIT. MatTek Corporation is at the forefront of tissue engineering and is a world leader in the production of innovative 3D reconstructed human tissue models.

EpiDerm™, MatTek’s first 3D human cell based in vitro model, was introduced in 1993 and became an immediate technical and commercial success. MatTek revolutionized the market for human cell-based in vitro models by:

  • Reducing the cost of such models by 50-80%
  • Optimizing researchers’ results by introducing published QC standards (concurrent positive and negative controls), assuring a level of reproducibility acceptable to industry and regulators.
  • Increasing industry and regulator confidence in the performance of commercially available in vitro tissue models.


MatTek’s human cell-derived tissue models are used throughout the United States and Canada, Europe, Japan, and Eastern Asia. Their record of scientific and technological innovation remains strong as they continue to develop and validate new in vitro assays and human tissue models.